Asymptotic analysis of the nonsteady micropolar fluid flow through a curved pipe

ABSTRACT

We consider the nonsteady flow of a micropolar fluid in a thin (or long) curved pipe via rigorous asymptotic analysis. Germano's reference system is employed to describe the pipe's geometry. After writing the governing equations in curvilinear coordinates, we construct the asymptotic expansion up to a second order. Obtained in the explicit form, the asymptotic approximation clearly demonstrates the effects of pipe's distortion, micropolarity and the time derivative. A detailed study of the boundary layers in space is provided as well as the construction of the divergence correction. Finally, a rigorous justification of the proposed effective model is given by proving the error estimates.     

Non‐enzymatic Ribonucleotide Reduction in the Prebiotic Context

Model studies of prebiotic chemistry have revealed compelling routes for the formation of the building blocks of proteins and RNA, but not DNA. Today, deoxynucleotides required for the construction of DNA are produced by reduction of nucleotides catalysed by ribonucleotide reductases, which are radical enzymes. This study considers potential non‐enzymatic routes via intermediate radicals for the ancient formation of deoxynucleotides. In this context, several mechanisms for ribonucleotide reduction, in a putative H₂S/HS^. environment, are characterized using computational chemistry. A bio‐inspired mechanistic cycle involving a keto intermediate and HSSH production is found to be potentially viable. An alternative pathway, proceeding through an enol intermediate is found to exhibit similar energetic requirements. Non‐cyclical pathways, in which HSS^. is generated in the final step instead of HS^., show a markedly increased thermodynamic driving force (ca. 70 kJ mol^?1) and thus warrant serious consideration in the context of the prebiotic ribonucleotide reduction.     

Determination of 5-nitroindazole using silver solid amalgam electrode

Monatshefte für Chemie - Chemical Monthly - The voltammetric behavior of 5-nitroindazole was investigated at polished (p-AgSAE) and at mercury meniscus-modified (m-AgSAE) silver solid amalgam...